clinical-variant-reporter

Classifies germline variants using ACMG/AMP guidelines, generating clinical-grade reports with evidence audit trails.

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92/100

Security score

The clinical-variant-reporter skill was audited on Jun 11, 2026 and we found 8 security issues across 1 threat category. Review the findings below before installing.

Categories Tested

Security Issues

low line 227

External URL reference

SourceSKILL.md

227	- [Richards et al. (2015)](https://pubmed.ncbi.nlm.nih.gov/25741868/) — ACMG/AMP standards and guidelines for the interpretation of sequence variants. Genet Med 17:405–424

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External URL reference

SourceSKILL.md

228	- [Rehm et al. (2013)](https://pubmed.ncbi.nlm.nih.gov/23887774/) — ACMG clinical laboratory standards for next-generation sequencing. Genet Med 15:733–747

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SourceSKILL.md

229	- [Miller et al. (2023)](https://pmc.ncbi.nlm.nih.gov/articles/PMC10524344/) — ACMG SF v3.2 list for reporting of secondary findings. Genet Med 25:100866

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External URL reference

SourceSKILL.md

230	- [Abou Tayoun et al. (2018)](https://pubmed.ncbi.nlm.nih.gov/30192042/) — PVS1 ACMG/AMP variant criterion recommendations. Human Mutation 39:1517–1524

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External URL reference

SourceSKILL.md

231	- [Li & Wang (2017)](https://pubmed.ncbi.nlm.nih.gov/28132688/) — InterVar: clinical interpretation of genetic variants. Am J Hum Genet 100:267–280

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External URL reference

SourceSKILL.md