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Clinvar Database

Queries NCBI ClinVar for variant significance, interprets classifications, and provides programmatic access for genomic medicine.

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Security score

The Clinvar Database skill was audited on Mar 7, 2026 and we found 8 security issues across 2 threat categories. Review the findings below before installing.

Categories Tested

Security Issues

medium line 53

Curl to non-GitHub URL

SourceSKILL.md
53curl "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=clinvar&term=BRCA1[gene]+AND+pathogenic[CLNSIG]&retmode=json"
low line 32

External URL reference

SourceSKILL.md
32Search ClinVar using the web interface at https://www.ncbi.nlm.nih.gov/clinvar/
low line 53

External URL reference

SourceSKILL.md
53curl "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=clinvar&term=BRCA1[gene]+AND+pathogenic[CLNSIG]&retmode=json"
low line 240

External URL reference

SourceSKILL.md
240- Web submission portal: https://submit.ncbi.nlm.nih.gov/subs/clinvar/
low line 350

External URL reference

SourceSKILL.md
350- ClinVar home: https://www.ncbi.nlm.nih.gov/clinvar/
low line 351

External URL reference

SourceSKILL.md
351- ClinVar documentation: https://www.ncbi.nlm.nih.gov/clinvar/docs/
low line 352

External URL reference

SourceSKILL.md
352- E-utilities documentation: https://www.ncbi.nlm.nih.gov/books/NBK25501/
low line 354

External URL reference

SourceSKILL.md
354- ClinGen expert panels: https://clinicalgenome.org/
Scanned on Mar 7, 2026
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